January 15, 2025

The Impact of Radiation Therapy on Ejaculation in Prostate Cancer Patients

Written by
Edward Calleja
Prostate Cancer
Erectile Problems
Wave Blue

Radiation therapy is a common treatment for prostate cancer, using high-energy radiation to kill cancer cells. While this treatment can be effective, it often comes with side effects that affect a man’s sexual health. Many men are concerned about erectile dysfunction (ED), which is the difficulty in getting or keeping an erection. Although radiation therapy can have better short-term sexual health outcomes compared to radical prostatectomy (surgical removal of the prostate), it still poses risks, including impacts on ejaculatory function.

How Does Radiation Therapy Affect Ejaculatory Function?

Ejaculatory function involves the release of semen during ejaculation and any associated sensations, including pain. Current research on how radiation therapy affects this function is limited. However, many men report reduced semen volume and pain during ejaculation after undergoing radiation therapy for prostate cancer.

What is Stereotactic Body Radiation Therapy (SBRT)?

Stereotactic Body Radiation Therapy (SBRT) is a highly precise form of radiation therapy that targets cancer cells while minimising damage to healthy tissue. This precision can reduce the risk of radiation-related ED, but its effects on ejaculatory function require further exploration. A recent study investigated this aspect.

Study on SBRT and Ejaculatory Function

A study conducted at Georgetown University Hospital examined the impact of SBRT on ejaculatory function in prostate cancer patients treated between 2013 and 2019. The study included 231 men, with an average age of 65 years.

How Was the Study Done?

Researchers used the Ejaculation Scale (ES-8) questionnaire to assess ejaculatory function before and after treatment. This questionnaire evaluates various aspects of ejaculation, including semen volume and pain. Scores range from 3 to 40, with lower scores indicating more severe problems.

What Did the Study Find?

The study found that men's ES-8 scores dropped slightly after starting SBRT but stabilised after the first month. Here are the average scores at different times:

  • Before treatment: 30.4
  • 1 month after treatment: 26.5
  • 3 months after treatment: 27.6
  • 6 months after treatment: 27.0
  • 9 months after treatment: 26.2
  • 12 months after treatment: 25.4
  • 18 months after treatment: 25.0
  • 24 months after treatment: 25.4

Men reported a decrease in the force of ejaculation and the amount of semen over time. Some men also experienced a sensation of ejaculation without any semen.

Discomfort and Bother

At the beginning of the study, 10% of the men reported some discomfort or bother with ejaculation, and 1% indicated moderate to severe problems. One month after starting SBRT, these figures increased to 35% and 8%, respectively.

What Do These Findings Mean for Prostate Cancer Patients?

These results suggest that men undergoing SBRT may experience changes in their ejaculatory function. It is crucial for patients to be aware of these potential side effects before starting treatment. While SBRT may have fewer negative effects on sexual health compared to other treatments, it still carries some risks.

Comprehensive Care for Prostate Cancer Patients

Prostate cancer patients require a comprehensive care plan that addresses all facets of their health. A holistic approach ensures that patients receive the necessary support throughout their treatment and recovery. This care model focuses on the integration of sexual, mental, and physical well-being, offering a well-rounded strategy for managing the complexities of prostate cancer treatment.

Sexual Health

Sexual health is a significant concern for many prostate cancer patients. Treatments like radiation therapy and surgery can impact sexual function, leading to issues such as erectile dysfunction (ED) and changes in ejaculatory function. It is essential to:

  • Provide Education: Inform patients about potential sexual side effects before treatment begins. This knowledge helps patients set realistic expectations and reduces anxiety.
  • Offer Solutions: Discuss treatment options for sexual dysfunction, such as oral medications, vitaros cream, vacuum devices, or counselling. Referrals to specialists like sex therapists can be beneficial.
  • Encourage Open Communication: Foster a supportive environment where patients feel comfortable discussing sexual health concerns with their healthcare team.

Mental Health

Mental health is another critical component of comprehensive care. A prostate cancer diagnosis and the subsequent treatment can be emotionally taxing, leading to stress, anxiety, and depression. Addressing mental health involves:

  • Psychological Support: Provide access to counselling and psychological services to help patients cope with the emotional aspects of their diagnosis and treatment.
  • Support Groups: Encourage participation in support groups where patients can share experiences and receive encouragement from others facing similar challenges.
  • Mind-Body Techniques: Introduce practices such as meditation, mindfulness, and relaxation techniques to help manage stress and improve overall well-being.

Physical Well-Being

Physical health is paramount in ensuring a patient’s recovery and quality of life during and after prostate cancer treatment. Key aspects include:

  • Exercise: Promote regular physical activity tailored to the patient's fitness level and treatment stage. Exercise can help reduce fatigue, improve mood, and enhance overall physical health.
  • Nutrition: Offer guidance on a balanced diet that supports recovery and overall health. Nutritional counselling can help manage side effects like weight loss or gain and gastrointestinal issues.
  • Monitoring and Management: Regular follow-ups to monitor the patient's physical health, manage side effects, and adjust treatment plans as necessary.

Coordination of Care

Effective coordination of care among various healthcare providers ensures that all aspects of a patient’s health are addressed. This involves:

  • Multidisciplinary Teams: Forming teams that include urologists, oncologists, radiologists, psychologists, and nutritionists to provide comprehensive care.
  • Patient-Centered Approach: Involving patients in their care decisions and respecting their preferences and values.
  • Continual Assessment: Regularly assessing and adjusting the care plan to address any new or ongoing issues.

Importance of Comprehensive Care

A comprehensive care approach is vital because it:

  • Enhances Quality of Life: By addressing the full spectrum of a patient's needs, comprehensive care improves overall quality of life.
  • Reduces Anxiety and Depression: Providing psychological support helps manage the emotional burden of cancer diagnosis and treatment.
  • Improves Outcomes: Coordinated care and early intervention in managing side effects can lead to better treatment outcomes and faster recovery.
  • Supports Long-Term Health: Ensuring that physical, sexual, and mental health needs are met helps patients maintain long-term well-being and reduces the risk of chronic conditions post-treatment.

Words of Wisdom from a Consultant Urologist

Prostate cancer treatment affects many parts of a man's life, especially his sexual health. Knowing about potential side effects and having a strong support system can make a big difference.