What is Bicalutamide, and how does it work?
Bicalutamide is an oral hormonal medication belonging to a class of drugs known as anti-androgens.
Androgens, like testosterone, are male hormones that can fuel the growth of prostate cancer cells.
Bicalutamide works by blocking the effects of androgens on cancer cells, slowing down their growth and potentially shrinking the tumour.
When is Bicalutamide prescribed?
Bicalutamide is primarily used with other prostate cancer treatments, such as surgery, radiation therapy, or as part of androgen deprivation therapy (ADT). It may also be recommended in cases where surgery or radiation therapy alone may not be enough to control the cancer.
What are the common side effects of Bicalutamide?
Like any medication, Bicalutamide may cause side effects. Common side effects include:
- Hot flashes
- Breast tenderness or enlargement
- Decreased libido (sex drive)
- Erectile dysfunction (difficulty achieving or maintaining an erection)
- Fatigue
- Nausea
- Constipation or diarrhoea
It's essential to discuss any side effects you experience with your doctor. They can help manage them or adjust your treatment if necessary.
How common is breast pain with Bicalutamide?
One common side effect of Bicalutamide, especially with the higher 150mg dose, is breast pain or tenderness. Some patients may also experience breast enlargement (gynecomastia). This occurs due to the anti-androgenic effects of Bicalutamide, which can interfere with the balance of hormones in the body.
It is essential to promptly report any breast pain or enlargement to your healthcare provider. While this side effect may be uncomfortable, it is generally not a sign of breast cancer. You have to seek medical attention immediately.
Your doctor may consider prescribing Tamoxifen, which can help prevent or alleviate breast pain caused by Bicalutamide or other anti-androgen treatments. The use of Tamoxifen should be discussed with your healthcare provider.
Can Bicalutamide cure prostate cancer?
Bicalutamide is not a cure for prostate cancer, but it can significantly slow down the growth of cancer cells and control the disease's progression. It is often used to keep the cancer under control, manage symptoms, and improve the quality of life for patients with advanced prostate cancer.
How do I take Bicalutamide?
Bicalutamide is typically taken orally as a tablet, and the dosage will depend on your specific condition and the treatment plan your doctor has recommended.
How much Bicalutamide can I take?
Bicalutamide is available in two doses: 50mg and 150mg tablets.
The 50mg dose is commonly combined with other early-stage prostate cancer therapies.
The 150mg dose is typically used for more advanced cases or when the cancer has spread beyond the prostate gland. The higher dose provides a more potent androgen-blocking effect but may also increase the risk of specific side effects.
Are there any interactions with other medications or supplements?
Bicalutamide may interact with other medications or supplements you are taking. Inform your doctor or pharmacist about all the medicines, vitamins, or herbal supplements you are using to avoid potential interactions that could affect the effectiveness of
Can I drink alcohol while taking Bicalutamide?
Moderate alcohol consumption is generally considered safe while taking Bicalutamide. However, excessive alcohol intake should be avoided as it may worsen specific side effects and overall health.
How long will I need to take Bicalutamide?
The duration of Bicalutamide treatment will depend on your specific medical condition and the stage of prostate cancer. Some patients may take it for a few months, while others may require longer-term treatment. Your doctor will monitor your progress and determine your most appropriate treatment duration.
Reflections from a consultant prostate cancer surgeon.
Bicalutamide is a valuable medication used in the management of prostate cancer. It works by slowing down the growth of cancer cells and can improve the quality of life for patients with prostate cancer.
